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CheckPoint Associate outline

DNA Replication and Checkpoint control in S part | 156-110 Practice Questions and Free test PDF

Alberts, B. DNA replication and recombination. Nature 421 431–435 (2003). doi:10.1038/nature01407.

Anderson, S. & DePamphilis, M. L. Metabolism of Okazaki fragments throughout simian virus forty DNA replication. The Journal of biological Chemistry 254 11495–11504 (1979).

Bailis, J.M. et al. Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote S-phase genome steadiness. Molecular and cellular Biology 28 1724–1738 (2008) doi:10.1128/MCB.01717-07.

Bochman, M.L. & Schwacha, A. 2008. The Mcm2-7 complicated has in vitro helicase undertaking. Molecular cellphone 31 287–293. doi:10.1016/j.molcel.2008.05.020.

Bochman, M.L. & Schwacha, A. 2009. The Mcm complex: unwinding the mechanism of a replicative helicase. Microbiol Mol Biol Rev 73 652–683. doi:10.1128/MMBR.00019-09.

Caspari, T. how to spark off p53. current Biology 10 R315–317 (2000) doi:10.1016/S0960-9822(00)00439-5.

Chattopadhyay, S. & Bielinsky, A. k. Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA harm. Molecular Biology of the mobilephone 18 4085–4095 (2007) doi: 10.1091/mbc.E06-12-1148.

Cimprich, k.A. & Cortez, D. 2008. ATR: a vital regulator of genome integrity. Nature experiences 9 616–627 (2007) doi:10.1038/nrm2450.

Cortez, D., Glick, G., & Elledge, S. J. Minichromosome preservation proteins are direct pursuits of the ATM and ATR checkpoint kinases. proceedings of the national Academy of Sciences of the us of the us a hundred and one 10078–10083 (2004) doi: 10.1073/pnas.0403410101.

Fien, ok. et al. 2004. Primer utilization through DNA polymerase alpha-primase is influenced through its interplay with Mcm10p. The Journal of biological Chemistry 279 16144–16153. doi: 10.1074/jbc.M512997200.

Forsburg, S.L. The MCM helicase: linking checkpoints to the replication fork. Biochemical Society Transactions 36 114–119 (2008).

Gambus, A. et al. A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha inside the eukaryotic replisome. The EMBO Journal 28 2992–3004 (2009) doi:10.1038/emboj.2009.226.

Hubscher, U., Maga, G., & Spadari, S. Eukaryotic DNA polymerases. Annual assessment of Biochemistry seventy one 133–163 (2002) doi:10.1146/annurev.biochem.71.090501.150041.

Katou, Y. et al. S-part checkpoint proteins Tof1 and Mrc1 form a sturdy replication-pausing complicated. Nature 424 1078–1083 (2003) doi:10.1038/nature01900.

Kouprina, N. et al. CTF4 (CHL15) mutants demonstrate faulty DNA metabolism within the yeast Saccharomyces cerevisiae. Molecular and mobile Biology 12 5736–5747 (1992).

Langston, L. D. & O'Donnell, M. DNA replication: retain relocating and do not intellect the hole. Molecular cellphone 23 one hundred fifty five–one hundred sixty (2006) doi:10.1016/j.molcel.2006.05.034.

Menoyo, A. et al. Somatic mutations in the DNA hurt-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. melanoma research sixty one 7727–7730 (2001).

service provider, A.M. et al. A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae. Molecular and cellular Biology 17 3261–3271 (1997).

Miles, J. & Formosa, T. facts that POB1, a Saccharomyces cerevisiae protein that binds to DNA polymerase alpha, acts in DNA metabolism in vivo. Molecular and cellular Biology 12 5724–5735 (1992).

Moldovan, G.L., Pfander, B., & Jentsch, S. PCNA, the maestro of the replication fork. phone 129 665–679 (2007) doi:10.1016/j.telephone.2007.05.003.

Moyer, S.E., Lewis, P.W. & Botchan, M.R. Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. lawsuits of the national Academy of Sciences of the united states of america 103 10236–10241 (2006) doi: 10.1073/pnas.0602400103.

Paulsen, R. D. et al. A genome-large siRNA monitor exhibits different cellular techniques and pathways that mediate genome stability. Molecular phone 35 228–239 (2009) doi:10.1016/j.molcel.2009.06.021.

Pizzagalli, A. et al. DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-delicate mutation, and protein homology with different DNA polymerases. complaints of the national Academy of Sciences of the us of the usa 85 3772–3776 (1988).

Remus, D. et al.. Concerted loading of Mcm2-7 double hexamers around DNA right through DNA replication beginning licensing. mobile 139 719–730 (2009) doi:10.1016/j.mobilephone.2009.10.015.




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